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    BMG多功能酶标仪国内用户出版物快报 (2021年3月)

    欢迎查阅伯齐科技为您整理的2021年3月份BMG多功能酶标仪国内用户发表的各方面研究的出版文章,往期的出版文章可在伯齐微信公众号回复:出版文章,查阅。有更多需求欢迎关注伯齐官方微信公众号留言。


    本期研究亮点推介


    >>>The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration

    浙江大学生科院徐平龙教授实验室近日在PLoS Biology杂志上发表肠道与肝脏再生功能相关研究成果:The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration。该研究揭示了首个靶向YAP的蛋白磷酸酶PPM1A,并阐明了PPM1A及其Hippo-YAP通路去磷酸化修饰在肠道和肝脏器官再生中的关键功能。BMG POLARstar Omega 多功能酶标仪广泛应用于生命科学基础研究,在此,通过双荧光素酶报告基因检测系统来分析相关转录活性,为文中主要的YAP转录激活功能分析提供解决方案。

    (原文:https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001122)


    研究领域

    (共计31篇,涉及20个领域)


    出版文章列表

    SS‐31 protect retinal pigment epithelial cells from H2O2‐induced cell injury by reducing apoptosis

    浙江大学医学院附属第四医院


    MIRLET7BHG promotes hepatocellular carcinoma progression by activating hepatic stellate cells through exosomal SMO to trigger Hedgehog pathway

    安徽医科大学第四附属医院肿瘤科


    A proof-of-concept study for the pathogenetic role of enhancer hypomethylation of MYBPHL in multiple myeloma

    香港中文大学生物医学学院


    Morphology/Interstitial Fluid Pressure-Tunable Nanopomegranate Designed by Alteration of Membrane Fluidity under Tumor Enzyme and PEGylation

    中国药科大学药学院


    Tannic acid/Fe3+ complex coated mesoporous silica nanoparticles for controlled drug release and combined chemo-photothermal therapy

    北京中医药大学中药学院


    Pinaverium Bromide Attenuates Lipopolysaccharide-Induced Excessive Systemic Inflammation via Inhibiting Neutrophil Priming

    南方医科大学基础医学院


    Structure-Based Design of a Selective Class I Histone Deacetylase (HDAC) Near-Infrared (NIR) Probe for Epigenetic Regulation Detection in Triple-Negative Breast Cancer (TNBC)

    中国药科大学药学院天然药物国家重点实验室和药物化学系


    Discovery of novel pyrimidine molecules containing boronic acid as VCP/p97 Inhibitors

    南京师范大学化学与材料科学学院生物医学功能材料国家与地方联合工程研究中心


    Lapatinib alleviates TOCP-induced axonal damage in the spinal cord of mouse

    中国科学院动物研究所分子毒理学实验室


    Inhibitory Effect of CADI on Melanin Transfer in the B16F10-HaCAT Cells Co-Culture System and Anti-Melanogenesis of CNCE in Zebrafish

    厦门大学生命科学学院


    Optimization of Extraction of Bioactive Compounds from Baphicacanthus cusia Leaves by Hydrophobic Deep Eutectic Solvents

    中山大学药学院


    The role of Src homology region 2 domain-containing phosphatase-1 hypermethylation in the classification of patients with myelodysplastic syndromes and its association with signal transducer and activator of transcription 3 phosphorylation in skm-1 cells

    河北大学附属医院血液科


    Human adenylate kinase 6 regulates WNK1 (with no lysine kinase-1) phosphorylation states and affects ion homeostasis in NT2 cells

    中国科学技术大学生命科学学院


    LncRNA PROX1-AS1 Facilitates Gastric Cancer Progression via miR-877-5p/PD-L1 Axis

    南京中医药大学附属常熟医院病理科


    Highly sensitive T1-T2dual-mode MRI probe based on ultra-small gadolinium oxide-decorated iron oxide nanocrystals

    安徽农业大学自然科学学院


    Glacial-interglacial sedimentation and paleocirculation at the Northwind Ridge, western Arctic Ocean

    自然资源部海底地球科学重点实验室


    Pyrvinium Treatment Confers Hepatic Metabolic Benefits via β-Catenin Downregulation and AMPK Activation

    中南大学湘雅医院临床药理学教研室


    Amyloid-β (25–35) regulates neuronal damage and memory loss via SIRT1/Nrf2 in the cortex of mice

    沈阳医学院生物化学与分子生物学系


    Taraxacum mongolicum extract inhibited malignant phenotype of triple-negative breast cancer cells in tumor-associated macrophages microenvironment through suppressing IL-10 / STAT3 / PD-L1 signaling pathways

    北京大学肿瘤医院研究所


    Increases of Lipophilic Antioxidants and Anticancer Activity of Coix Seed Fermented by Monascus purpureus

    贵州大学生命科学学院/农业生物工程研究所


    G-quadruplex RNA motifs influence gene expression in the malaria parasite Plasmodium falciparum

    香港中文大学生命科学学院和农业生物技术国家重点实验室


    Circular RNA Circ-BANP Regulates Oxidized Low-density Lipoprotein-induced Endothelial Cell Injury Through Targeting the miR-370/Thioredoxin-interacting Protein Axis

    中国人民解放军920联合后勤保障部队医院心内科


    The altered expression of neurofilament in mouse models and patients with spinal muscular atrophy

    中国医科大学附属医院神经内科


    Structural and biochemical insights into the recognition of RNA helicase CGH-1 by CAR-1 in C. elegans

    中国科学技术大学生命科学学院生命科学学院


    Pan-cancer investigation reveals mechanistic insights of planar cell polarity gene Fuz in carcinogenesis

    香港中文大学生命科学学院生命科学学院


    Ssrp1 Promotes Lung Cancer Progression By Blocking The Wnt Pathway and Is Negatively Regulated By Mirna-28-5p

    吉林大学第一医院


    Neuroprotective effect of ketamine against TNF‐α‐induced necroptosis in hippocampal neurons

    厦门大学医学院附属厦门大学湘安医院护理科


    PDZD8 mediated lipid transfer at ER-LE/lys contacts is required for LE/lys positioning and neurite outgrowth

    华中科技大学同济医学院基础医学院生物化学与分子生物学系


    The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration

    浙江大学生命科学研究院


    New Insights Into the Antibacterial Mechanism of Cryptotanshinone, a Representative Diterpenoid Quinone From Salvia miltiorrhiza Bunge

    江中医药大学分子医学研究所生命科学学院


    Silencing of circular RNA circPDE5A suppresses neuroblastoma progression by targeting the miR-362-5p/NOL4L axis.

    福建医科大学附属第二医院儿科


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