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    BMG多功能酶标仪国内用户出版物快报 (2024年2月)

    欢迎查阅进科驰安为您整理的2024年2月份BMG多功能酶标仪国内用户发表的各方面研究的出版文章,往期的出版文章可在进科驰安微信公众号回复:出版文章,查阅。有更多需求欢迎关注进科驰安官方微信公众号留言。



    本期研究亮点推介

    >>>TAK-242 improves sepsis-associated acute kidney injury in rats by inhibiting the TLR4/NF-κB signaling pathway


    山西省医学科学院山西白求恩医院危重病科,山西医科大学第三医院山西同济医院,

    华中科技大学同济医学院同济医院联合在专业学术期刊Renal Failure发表了题为TAK-242 improves sepsis-associated acute kidney injury in rats by inhibiting the TLR4/NF-κB signaling pathway的文章,研究发现TAK-242可以通过抑制TLR4/NF-κB信号通路的活性来改善氧化应激、线粒体功能障碍和炎症反应,从而预防脓毒症相关急性肾损伤。

    科研工作者借助BMG的PHERAstar FSX高通量读板机检测肾损伤水平,氧化应激水平,炎症因子水平以及线粒体损伤。BMG的PHERAstar FSX高通量读板机专为高通量药物筛选设计,拥有3个光源,4个两两成对的PMT检测器,可以同时检测双波长发射,非常适合药物筛选常用的BRET,FRET,HTRF,FP检测技术,拥有非常稳定的数据检测结果和超快的检测速度,为高通量筛选提供强大且稳定的筛选平台。

    (原文:https://www.tandfonline.com/doi/full/10.1080/0886022X.2024.2313176


    研究领域

    (共计26篇,涉及19个领域)


    出版文章列表

    Impact of scandium and terbium on the mechanical properties, corrosion behavior, and biocompatibility of biodegradable Mg-Zn-Zr-Mn alloys

    温州医科大学口腔医学院


    Hypoxia-activated selectivity-improved anti-PKM2 antibody combined with prodrug TH-302 for potentiated targeting therapy in hepatocellular carcinoma

    南开大学医学院细胞生物学教研室


    SNAT2-mediated regulation of estrogen and progesterone in the proliferation of goat mammary epithelial cells

    华中农业大学动物医学院


    In vitro anti-Helicobacter pylori activity and the underlining mechanism of an empirical herbal formula – Hezi Qingyou

    中山大学药学院


    Acetylcholine Analog-Modified Albumin Nanoparticles for the Enhanced and Synchronous Brain Delivery of Saponin Components of Panax Notoginseng

    昆明理工大学生命科学与技术学院


    Spiders Use Structural Conversion of Globular Amyloidogenic Domains to Make Strong Silk Fibers

    苏州大学生物与医学研究所


    Damage of polyethylene microplastics on the intestine multilayer barrier, blood cell immune function and the repair effect of Leuconostoc mesenteroides DH in the large-scale loach (Paramisgurnus dabryanus)

    河南师范大学生命科学学院


    High density mapping of durable and broad-spectrum stripe rust resistance gene Yr30 in wheat

    西北农林科技大学


    Syringaresinol Alleviates Early Diabetic Retinopathy by Downregulating HIF-1α/VEGF via Activating Nrf2 Antioxidant Pathway

    天津协和医疗中心


    Cross-Phosphorylation between AgrC Histidine Kinase and the Noncognate Response Regulator Lmo1172 in Listeria monocytogenes under Benzalkonium Chloride Stress

    新乡学院生物工程学院


    TAK-242 improves sepsis-associated acute kidney injury in rats by inhibiting the TLR4/NF-κB signaling pathway

    山西省医学科学院山西白求恩医院危重病科


    Multifunctional gelatin nanoparticle stabilized-Pickering emulsion hydrogel based on dextran and amikacin with controlled drug release and enhanced antibacterial capability for promoting infected wound healing

    西南交通大学医学院


    Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses

    中国科学院上海药物研究所药物研究国家重点实验室


    Structure-Guided Discovery of PD-1/PD-L1 Interaction Inhibitors: Peptide Design, Screening, and Optimization via Computation-Aided Phage Display Engineering

    卫生福利部中药研究所


    Effect of Eriocalyxin B on prostatic inflammation and pelvic pain in a mouse model of experimental autoimmune prostatitis

    安徽医科大学第一附属医院泌尿外科


    Experimental warming accelerates positive soil priming in a temperate grassland ecosystem

    清华大学环境学院环境模拟与污染控制国家重点联合实验室


    Villosol reverses 5-FU resistance in colorectal cancer by inhibiting the CDKN2A gene regulated TP53-PI3K/Akt signaling axis

    北方战区总医院药剂科


    Azetidines Kill Multidrug-Resistant Mycobacterium tuberculosis without Detectable Resistance by Blocking Mycolate Assembly

    中国科学院广州生物医药与健康研究所


    A ZBP1 isoform blocks ZBP1-mediated cell death

    厦门大学生命科学学院


    Design, synthesis, and biological evaluation of gambogenic acid derivatives: Unraveling their anti-cancer effects by inducing pyroptosis

    上海中医药大学药学院


    Chronic alcohol exposure induces cerebral microbleeds by TGF-β1/Smad signaling pathway mediated remodeling of cerebral small vessels

    中山大学孙逸仙纪念医院神经内科


    Mapping and identification of a reverse mutation of Rht2 that enhances plant height and thousand grain weight in an elite wheat mutant induced by spaceflight

    烟台大学生命科学学院植物分子与发育生物学重点实验室


    Dynamic phenotypic reprogramming and chemoresistance induced by lung fibroblasts in small cell lung cancer

    吉林省肿瘤医院肿瘤医学转化研究室


    Knockdown of liver cancer cell-secreted exosomal PSMA5 controls macrophage polarization to restrain cancer progression by blocking JAK2/STAT3 signaling

    宁波市第二医院整形外科


    Chemiluminescent Poly(sodium 4-styrenesulfonate)-Encapsulated Acridinium Sulfonamide-Functionalized CoFe2O4 Nanoparticles for Detection of Cholesterol

    中国科学技术大学化学系精密与智能化学重点实验室


    The opposite role of lactate dehydrogenase a (LDHA) in cervical cancer under energy stress conditions

    东北师范大学国家药监局细胞与基因治疗药物产品质量控制重点实验室





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