BMG多功能酶标仪国内用户出版物快报 (2023年6月)
本期研究亮点推介
>>>Syzygium aromaticum enhances innate immunity by triggering macrophage M1 polarization and alleviates Helicobacter pylori-induced inflammation
中山大学药学院,山东省国际制药工程实验室,鲁南药业集团有限公司,天津亿诺生物医药有限公司近日联合专业学术期刊Journal of Functional Foods发表了学术研究成果:Syzygium aromaticum enhances innate immunity by triggering macrophage M1 polarization and alleviates Helicobacter pylori-induced inflammation,研究丁香干芽对先天免疫和幽门螺杆菌感染相关炎症具有的潜在影响,阐明其具体作用,尤其是分子机制。研究人员选用了德国的BMG Labtech CLARIOstar plus多功能酶标仪对细胞活力、吞噬速率、NO含量以及细胞因子水平进行了分析。结果表明,丁香干芽水提取物增加了吞噬速率和细胞因子表达水平,同时激活了TLR4/MyD88介导的NF-κB和MAPK通路,降低了Nrf2/HO-1信号传导,还阻止了幽门螺杆菌感染的RAW 264.7和GE产生的促炎物质的释放。BMG Labtech CLARIOstar plus多功能酶标仪配备全波长超快速光吸收静息光栅和专利的LVF荧光光栅,能自由选择光吸收检测波长和荧光检测所需的激发和发射波长以及相应带宽,同时还具有媲美于滤光片检测灵敏度,非常适合开展多种实验项目研究。
(原文:https://www.sciencedirect.com/science/article/pii/S1756464623002268)
研究领域
(共计33篇,涉及28个领域)
Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists
中国科学技术大学第一附属医院内分泌与代谢疾病研究所内分泌科
The effect of semen cuscutae flavonoid on Sertoli cells and blood-testis barrier in male infertility: integrating network pharmacology and experimental verification
北京中医药大学中医学院
Comparative study on optimization of NADES extraction process by dual models and antioxidant activity of optimum extraction from Chuanxiong-Honghua
浙江中医药大学
A Novel highly selective allosteric inhibitor of TYK2 can block inflammation/autoimmune pathways
上海齐鲁制药研究中心有限公司
Molecular identification and validation of four stable QTL for slow-mildewing resistance in Chinese wheat cultivar Bainong 64
西北农林科技大学农学院
HLA-E-restricted SARS-CoV-2-specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation
中国医科大学第一附属医院检验医学部艾滋病免疫重点实验室
CLDN18.2 and 4-1BB bispecific antibody givastomig exerts antaitumor activity through CLDN18.2-expressing tumor-directed T-cell activation
安徽医科大学第一附属医院
A sandwich ELISA for the detection of mollusks and mollusk products
台北医科大学食品安全硕士班
Syzygium aromaticum enhances innate immunity by triggering macrophage M1 polarization and alleviates Helicobacter pylori-induced inflammation
中山大学药学院
Pteryxin suppresses osteoclastogenesis and prevents bone loss via inhibiting the MAPK/Ca2+ signaling pathways mediated by ROS
广西医科大学省部共建再生医学与医用生物资源开发与应用协同创新中心
Mechanistic Insight into the Inhibitory Activity of Elasnin-Based Coating against Early Marine Biofilms
南方海洋科学与工程广东省重点实验室(广州)
Highly-specific aptamer targeting SARS-CoV-2 S1 protein screened on an automatic integrated microfluidic system for COVID-19 diagnosis
国立清华大学动力机械工程系
miR-125b-5p alleviates the damage of myocardial infarction by inhibiting the NFAT2 to reduce F2RL2 expression
天津大学医学工程与转化医学研究院
Disruption of the Clock Component Bmal1 in Mice Promotes Cancer Metastasis through the PAI-1-TGF-β-myoCAF-Dependent Mechanism
中山大学附属第一医院妇产科
A Role for Microsomal Glutathione Transferase 1 in Melanin Biosynthesis and Melanoma Progression.
大连理工大学生命与制药学院
Synergistic effect of drug/antibiotic-impregnated micro/nanohybrid mesoporous bioactive glass/calcium phosphate composite bone cement on antibacterial and osteoconductive activities
逢甲大学纤维与复合材料系先进医疗器械与复合材料实验室
Sensitivity of Puccinia triticina f. sp. tritici from China to Triadimefon and Resistance Risk Assessment
西北农林科技大学干旱地区作物胁迫生物学国家重点实验室/植物保护学院
Potential of bacteriophage therapy in managing Staphylococcus aureus infections during chemotherapy for lung cancer patients
香港中文大学药学院
Isomerization of bioactive acylhydrazones triggered by light or thiols
青岛大学药学院药物化学系
CircEGFR reduces the sensitivity of pirarubicin and regulates the malignant progression of triple-negative breast cancer via the miR-1299/EGFR axis
吉林大学药学院实验药理与毒理学教研室
In-situ real-time monitoring of chemical kinetics by an automated micro-reaction device
大连海事大学辽宁省海洋传感与智能检测重点实验室
Polysaccharides from Dioscorea opposita Thunb.: isolation, structural characterization, and anti-inflammatory and anti-tumor effects against hepatocellular carcinoma
河南大学化学与分子科学学院生命科学学院
Epitope-Directed Antibody Elicitation by Genetically Encoded Chemical Cross-Linking Reactivity in the Antigen
中国科学院生物物理研究所蛋白质与多肽药物重点实验室
Gemcitabine‑fucoxanthin combination in human pancreatic cancer cells
上海应用技术学院香水与香气技术学院
Isolation of Anti-SARS-CoV-2 Natural Products Extracted from Mentha canadensis and the Semi-synthesis of Antiviral Derivatives
国立台湾大学医学院临床检验与医学生物技术学系
20(R)-ginsenoside Rg3-loaded polyurethane/marine polysaccharide based nanofiber dressings improved burn wound healing potentials
沈阳药科大学武亚创新学院
Uncovering the virome and its interaction with antibiotic resistome during compost fertilization
清华大学环境学院环境模拟与污染控制国家重点联合实验室
Identification of DNA repair gene signature and potential molecular subtypes in hepatocellular carcinoma
辽宁盘锦辽油宝石花医院风湿病免疫科
Multiple-statistical genome-wide association analysis and genomic prediction of fruit aroma and agronomic traits in peaches
上海市农业科学院林业果树研究所
MiR-29a-3p promotes nasal epithelial barrier dysfunction via direct targeting of CTNNB1-VCL module in allergic rhinitis
首都医科大学宣武医院耳鼻咽喉头颈外科
Development and In Vitro Analysis of Layer-by-Layer Assembled Membranes for Potential Wound Dressing: Electrospun Curcumin/Gelatin as Middle Layer and Gentamicin/Polyvinyl Alcohol as Outer Layers
丰甲大学纤维与复合材料系先进医疗器械与复合材料实验室
The DRD2 antagonist haloperidol mediates autophagy-induced ferroptosis to increase temozolomide sensitivity by promoting endoplasmic reticulum stress in glioblastoma
广州南方医院
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