BMG多功能酶标仪国内用户出版物快报 (2024年8月)
本期研究亮点推介
>>>LARP1, an RNA-binding protein, participates in ovarian cancer cell survival by regulating mitochondrial oxidative phosphorylation in response to the influence of the PI3K/mTOR pathway
本期天然药相关研究成果显著增加,有5篇关于天然药药理学的研究论文,1篇天然药物结构和药效关系的论文,还有1篇中药药理学的研究论文。关于细胞能量代谢的研究论文有2篇。其中,吉林大学基础医学院病理生理学教育部重点实验室在专业学术期刊Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease发表的题为LARP1, an RNA-binding protein, participates in ovarian cancer cell survival by regulating mitochondrial oxidative phosphorylation in response to the influence of the PI3K/mTOR pathway的文章,对于肿瘤治疗的研究具有参考意义。
科研工作者使用BMG的CLARIOstar多功能酶标仪,使用 MitoXpress® Xtra-Oxygen Consumption 测定法测量细胞氧化磷酸化OCR,评估线粒体功能。采用ATP 生物发光测定试剂盒用于测量细胞中 ATP 的水平,使用BMG的Omega酶标仪测量发射光,将计数归一化为蛋白质浓度。CLARIOstar多功能酶标仪具有专属的细胞能量代谢检测配置、检测方案和分析方案,轻松实现高通量细胞能量代谢检测,Omega酶标仪能灵敏的检测发光信号,用于细胞活力检测。BMG的多功能酶标仪提供多种实验分析方案,是药物作用机理,疾病治疗靶点研究的有力工具。
(原文:https://www.sciencedirect.com/science/article/abs/pii/S0925443924004460)
研究领域
(共计34篇,涉及21个领域)
Virulence, structure, and triadimefon sensitivity of the Puccinia striiformis f. sp. tritici population in Shaanxi Province, China
西北农林科技大学植物保护学院
Sympathetic neuropeptide Y protects from obesity by sustaining thermogenic fat
北京体育大学体育科学学院
Differential effect of lead and cadmium on mitochondrial function and NLRP3 inflammasome activation in human trophoblast
汕头大学医学院环境医学与发育毒理学实验室
Duality of H2O2 detoxification and immune activation of Ralstonia solanacearum alkyl hydroperoxide reductase C (AhpC) in tobacco
青岛农业大学植物健康与医药学院
Inoculation of Paraburkholderia sp. GD17 improves seedling growth and tolerance to Cadmium in Chinese cabbage
沈阳师范大学生命科学学院
Juzaowan Suppresses Glycolysis in Breast Cancer Cells by Inhibiting the STAT3/C-Myc Axis
福建医科大学南平第一医院甲状腺乳房外科
Tumor-associated macrophage-derived itaconic acid contributes to nasopharyngeal carcinoma progression by promoting immune escape via TET2
中南大学湘雅第二医院耳鼻咽喉头颈外科
Development of Nitric Oxide Releasing Oxoisoaporphines with Antidepressant Activities by Simultaneously Regulating MAO-A and SERT
中国药科大学中药学院天然药物化学系天然药物国家重点实验室
Functional characterisation and modification of a novel Kunitzin peptide for use as an anti-trypsin antimicrobial peptide against drug-resistant Escherichia coli
中国农业科学院
Suppression of inner blood-retinal barrier breakdown and pathogenic Müller glia activation in ischemia retinopathy by myeloid cell depletion
中山大学眼科国家重点实验室
Carnosic acid, a novel food-source AT1R antagonist and its anti-hypertension mechanism华南师范大学生命科学学院广东省植物发育生物技术重点实验室
A novel evaluation mode of Nao An Capsules using multi-wavelength fusion fingerprint combined with quantitative analysis of multi-components by a single marker method and antioxidant activity
河北医科大学第一医院临床药剂科
The adhesin RadD enhances Fusobacterium nucleatum tumour colonization and colorectal carcinogenesis
上海交通大学医学院仁济医院
Synthesis of the Corrected Structure Assigned to Clonorosin B, an Alkaloid Obtained from the Soil-derived Fungus Clonostachys rosea YRS-06
广东医科大学海洋生物医学研究所广东省天然药物研究与开发重点实验室
Oral secretions from striped stem borer (Chilo suppressalis) induce defenses in rice
江苏省农业科学院植物保护研究所
Repurposing cetylpyridinium chloride and domiphen bromide as phosphoethanolamine transferase inhibitor to combat colistin-resistant Enterobacterales
江苏大学医学院检验医学系
An acidic polysaccharide promoting GLP-1 secretion from Dendrobium huoshanense protocorm-like bodies: Structure validation and activity exploration
合肥工业大学食品与生物工程学院
A diazeniumdiolate signal in Pseudomonas syringae upregulates virulence factors and promotes survival in plants
中国农业大学植物保护学院
Structural analysis of the human C5a-C5aR1 complex using cryo-electron microscopy
南昌大学江西医学院基础医学院教育部实体肿瘤靶向治疗基础研究与创新中心
Asiatic acid ameliorates doxorubicin-induced cardiotoxicity by promoting FPN-mediated iron export and inhibiting ferroptosis
复旦大学附属中山医院心内科
Synergism of colistin and globular endolysins against multidrug-resistant gram-negative bacteria
香港中文大学医学院药学院
The SPARC-related modular calcium binding 1 (Smoc1) regulated by androgen is required for mouse gubernaculum development and testicular descent
吉林大学第一医院男科
Network Pharmacology Followed by Experimental Validation to Explore the Mechanism of Stigmasterol in Sangbaipi Decoction Regulating PI3K/Akt Signaling to Alleviate Acute Exacerbation of Chronic Obstructive Pulmonary Disease
杭州市同德医院肺重症医学科
Characterization of a KPC-84 harboring Klebsiella pneumoniae ST11 clinical isolate with ceftazidime-avibactam resistance
四川大学华西医院感染性疾病中心
Optimising corn (Zea mays) cob powder as an effective sorbent for diverse gel matrices: exploring particle size and powder concentration effects
南京农业大学食品科学与技术学院,肉类加工与质量控制重点实验室
ASA VI controls osteoarthritis in mice by maintaining mitochondrial homeostasis through Sirtuin 3
湖北省中医医院骨科
Treatment with autophagic inhibitors enhances oligonol‑induced apoptotic effects in nasopharyngeal carcinoma cells
中国医科大学医学院医学院
The MondoA-dependent TXNIP/GDF15 axis predicts oxaliplatin response in colorectal adenocarcinomas
重庆大学三峡医院临床研究中心(CRC)
Toxic effects of sodium hypochlorite as disinfectants on human bronchial epithelial cells
西安建筑科技大学环境与市政工程学院
LARP1, an RNA-binding protein, participates in ovarian cancer cell survival by regulating mitochondrial oxidative phosphorylation in response to the influence of the PI3K/mTOR pathway
吉林大学基础医学院病理生理学教育部重点实验室
Nonlinear Impacts of Temperature on Antibiotic Resistance in Escherichia coli
厦门大学环境与生态学院
New CDDO Arylboronate Ester Derivatives with High Selectivity and Low Toxicity
中国药科大学中药学院天然药物化学系天然药物国家重点实验室
Triggering of endoplasmic reticulum stress via ATF4-SPHK1 signaling promotes glioblastoma invasion and chemoresistance
吉林大学中日联合医院神经外科
Dihydroartemisinin restores the immunogenicity and enhances the anticancer immunosurveillance of cisplatin by activating the PERK/eIF2α pathway
华中科技大学同济医学院协和医院
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