BMG多功能酶标仪国内用户出版物快报 (2024年1月)
本期研究亮点推介
>>>The metabolic role of the CD73/adenosine signaling pathway in HTR-8/SVneo cells: A Double-Edged Sword?
重庆医科大学第一附属医院妇产科,重庆医科大学加拿大-中国-新西兰母胎医学联合实验室,重庆市重大代谢疾病转化医学重点实验室和重庆医科大学第二附属医院妇产科联合在专业学术期刊Heliyon发表了题为The metabolic role of the CD73/adenosine signaling pathway in HTR-8/SVneo cells: A Double-Edged Sword?的文章,研究CD73/腺苷信号通路在滋养层细胞增殖和迁移中的代谢作用。他们通过RNA-seq、代谢组学和能量代谢研究结果表明,腺苷处理抑制有氧呼吸、糖酵解和氨基酸合成,并增加短链脂肪酸(SCFAs)的利用率。他们研究结果表明,腺苷在调节滋养层能量代谢中的作用就像一把双刃剑——要么抑制有氧呼吸,要么向代谢通量中补充碳源。CD73/腺苷信号通过调节能量代谢来调节滋养层EMT、迁移和增殖。
科研工作者借助BMG的CLARIOstar Plus读板机进行细胞能量代谢。BMG的meta-ready细胞能量代谢检测仪能兼容各种样本,如贴壁细胞、悬浮细胞、线粒体、细菌、3D培养细胞等,预设了耗氧率OCR和酸化率ECAR的检测程序和分析程序,一键检测和获取数据,帮助研究人员轻松进行细胞能量代谢研究。
(原文:https://www.sciencedirect.com/science/article/pii/S2405844024012830)
研究领域
(共计35篇,涉及20个领域)
The metabolic role of the CD73/adenosine signaling pathway in HTR-8/SVneo cells: A Double-Edged Sword?
重庆医科大学第一附属医院妇产科
Drug-induced interstitial lung disease: a real-world pharmacovigilance study of the FDA Adverse Event Reporting System from 2004 to 2021
陆军军医大学大坪医院药剂科
CircZCCHC2 decreases pirarubicin sensitivity and promotes triple-negative breast cancer development via the miR-1200/TPR axis
吉林大学第一医院普通外科中心乳腺外科
Virulence and Molecular characterization reveal sign of sexual genetic recombination of Puccinia striiformis f. sp. tritici and Puccinia striiformis f. sp. hordei in Tibet
西北农林科技大学植物保护学院
Interacting effects of water and nitrogen addition on soil–plant sulfur dynamics in a semi-arid grassland
河北大学生命科学学院
Mammary epithelial cell-derived exosomal miR-155-inhibitor played a key role in the treatment of mastitis via down-regulation of TLRs/NF-κB signaling pathway to inhibit inflammatory response
江苏农牧职业学院宠物技术学院
Chiral S-flurbiprofen axetil-loaded lipid microspheres for improved analgesic effects: Preparation, characterization, and preclinical evaluation
上海交通大学药学院
Increased expression of SSEA-4 on TKI-resistant non-small cell lung cancer with EGFR-T790M mutation
中央研究院基因组学研究中心
Inhibitory effects of naringenin on estrogen deficiency-induced obesity via regulation of mitochondrial dynamics and AMPK activation associated with white adipose tissue browning
台湾台北市国防医疗中心三科总医院内科心内科
Mechanism of geraniol against E. coli infection by regulating YDIV
成都医学院
Genetic Analysis of Adaptive Traits in Spring Wheat in Northeast China
黑龙江省农业科学院作物资源研究所
A New Synthesized Dicarboxylated Oxy-Heparin Efficiently Attenuates Tumor Growth and Metastasis
深圳海普瑞药业集团有限公司
Intracellular Delivery of Piezotronic-Dominated Nanocatalysis to Mimic Mitochondrial ROS Generation for Powering Macrophage Immunotherapy
山东大学齐鲁医学院口腔医学院生物材料系
The cAMP Receptor Protein Gene Contributes to Growth, Stress Resistance, and colonization of Actinobacillus pleuropneumoniae
华中农业大学动物医学院
Storage stability of lysostaphin solution and its pulmonary delivery
香港中文大学医学院药学院
Antioxidant activity of spirostanol saponins from Allii Macrostemonis Bulbus and their contents in different origins and processed products
吉林农业大学中药学院中医系
Heme-Inducing Endothelial Pyroptosis Plays a Key Role in Radiofrequency Ablation of Hepatic Hemangioma Leading to Systemic Inflammatory Response Syndrome
首都医科大学附属北京朝阳医院肝胆外科
Bioenergetic Metabolism Modulatory Peptide Hydrogel for Cardiac Protection and Repair After Myocardial Infarction
中国医学科学院北京协和医学院生物医学工程研究所先进医用材料与器件国家重点实验室
Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy
百济神州(北京)有限公司
Therapeutic effects of coptisine derivative EHLJ7 on colorectal cancer by inhibiting PI3K/AKT pathway
中国医学科学院北京协和医学院药物研究所消化健康国家重点实验室
The Effects of Tachykinin1 Gene Products on Prepubertal Dabry’s Sturgeon (Acipenser dabrynus) Pituitary Hormone Secretion and Gene Expression
三峡工程湖北省鱼类保护重点实验室
Unveiling a Novel Mechanism for Competitive Advantage of Ciprofloxacin-Resistant Bacteria in the Environment through Bacterial Membrane Vesicles
暨南大学生命与健康工程研究所
Nitrogen Addition Enhances Soil Nitrogen Mineralization Through an Increase in Mineralizable Organic Nitrogen and the Abundance of Functional Genes
中国林业科学研究院生态与自然保护研究所
Surface Wrinkled Microsphere Enhanced Irregular Wound Healing Through Synergistic Hygroscopicity, Reversible Wet-Adhesion and Antibacterial Properties
国家纳米科学技术中心
The pleiotropic enhancer enh9 promotes cell proliferation and migration in non-small cell lung cancer via ERMP1 and PD-L1
北京航空航天大学工程医学院
Enhancing osteogenic differentiation of MC3T3-E1 cells during inflammation using UPPE/b-TCP/TTC composites via the Wnt/b-catenin pathway
华中科技大学同济医学院同济医院口腔科
PtuA and PtuB assemble into an inflammasome-like oligomer for anti-phage defense
四川大学华西医院肿瘤中心生物治疗科
Pyroptotic Macrophage-Derived Microvesicles Accelerate Formation of Neutrophil Extracellular Traps via GSDMD-N-expressing Mitochondrial Transfer during Sepsis
中山大学第五附属医院感染与免疫中心
The Osmolality and Hemolysis of High-Concentration Monoclonal Antibody Formulations
浙江大学药学院药物代谢与药物分析研究所
Preparation and synbiotic interaction mechanism of microcapsules of Bifidobacterium animalis F1–7 and human milk oligosaccharides (HMO)
华中农业大学食品科技学院
Stachydrine represses the proliferation and enhances cell cycle arrest and apoptosis of breast cancer cells via PLA2G2A/DCN axis
北京中医药大学东方医院乳腺科
Circular RNA CircACAP2 regulates temporomandibular joint osteoarthritis via miR-21-5p/PLAG1 axis
宁波大学第一附属医院口腔科
DTX2 promotes glioma development via regulation of HLTF
山西医科大学第一医院急诊科
Interventing mitochondrial PD-L1 suppressed IFN-γ-induced cancer stemness in hepatocellular carcinoma by sensitizing sorafenib-induced ferroptosis
厦门大学公共卫生学院
MiR-9 promotes G-MDSC recruitment and tumor proliferation by targeting SOCS3 in breast cancer
中国药科大学生命科学与技术学院
The chemical profiling and identification of Abelia macrotera (Graebn. et Buchw.) Rehd. based on UHPLC-Q-Exactive Orbitrap MS and study their antioxidant, anti-tyrosinase and anti-inflammatory activities
湖南医科大学药学院
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