BMG多功能酶标仪国内用户出版物快报 (2022年8月)
本期研究亮点推介
>>>Structure-based virtual screening discovers novel kidney-type glutaminase inhibitors
台北医科大学研究团队在顶尖学术期刊Biomedicine & Pharmacotherapy上发表研究成果,Structure-based virtual screening discovers novel kidney-type glutaminase inhibitors。研究团队建立了虚拟筛选技术,筛选药物作用靶点,发现了3个潜在的肿瘤治疗靶点,采用德国BMG公司的CLARIOstar多功能读板机助力关键酶活性研究验证。BMG的CLARIOstar读板机采用了灵活的LVF光栅技术,方便研究人员使用任何波长和带宽进行荧光检测,特别适用于药物早期研发研究。
(原文:https://www.sciencedirect.com/science/article/pii/S075333222200974X)
研究领域
(共计19篇,涉及16个领域)
Effect and mechanism of peanut skin proanthocyanidins on gliadin-induced Caco-2 celiac disease model cells
河南农业大学动物医学院
Effect of Puerarin on Osteogenic Differentiation in vitro and on New Bone Formation in vivo
山东大学
Lab-Attenuated Rabies Virus Facilitates Opening of the Blood-Brain Barrier by Inducing Matrix Metallopeptidase 8
华中农业大学农业微生物学国家重点实验室
Structure-based virtual screening discovers novel kidney-type glutaminase inhibitors
台北医科大学医学科技学院癌症生物学与药物发现研究所
A variant NS1 protein from H5N2 avian influenza virus suppresses PKR activation and promotes replication and virulence in mammals
国立中兴大学微生物与公共卫生研究所
Preparation and structure-activity relationship of highly active black garlic polysaccharides
齐鲁工业大学(山东省科学院)生物研究所
Induced mutation in ELONGATED HYPOCOTYL5 abolishes anthocyanin accumulation in the hypocotyl of pepper
华中农业大学园艺植物生物学教育部重点实验室
The Plasmodium falciparum Nuclear Protein Phosphatase NIF4 Is Required for Efficient Merozoite Invasion and Regulates Artemisinin Sensitivity
中国医科大学基础医学院免疫学系
Self-assembled terbium-amino acid nanoparticles as a model for terbium biosafety and bone repair ability assessment
山东大学齐鲁医学院
Pharmacological induction of AMFR increases functional EAAT2 oligomer levels and reduces epileptic seizures in mice
医学分子生物学国家重点实验室
Interstitial pneumonitis associated with EGFR/ ALK tyrosine kinase inhibitors used in non-small cell lung cancer: an observational, retrospective, pharmacovigilance study
首都医科大学北京朝阳医院药剂科
Blockade of STAT3/IL-4 overcomes EGFR T790M-cis-L792F-induced resistance to osimertinib via suppressing M2 macrophages polarization
中国医学科学院北京协和医学院国家肿瘤中心
A Novel Pectin-Like Glycopeptide Isolated from the Fruit of Fructus Mori Impedes Aggregation and Production of Aβ42
中国科学院上海药物研究所
Glycerol modified poly(vinyl alcohol)/poly(ethylene glycol) self-healing hydrogel for artificial cartilage
西安工业大学机械与电子工程学院机械与生物医学工程组
Enhancement of the c ytotoxic effect of dihydroartemisinin in high-riskhuman papillomavirus-infected cells by aminolevulinic acid via the Bax/Bcl-2-caspase pathway
南方医科大学南方医院皮肤性病科
Continuous Fermentation by Lactobacillus bulgaricus T15 Cells Immobilized in Cross-Linked F127 Hydrogels to Produce ᴅ-Lactic Acid
吉林农业大学生命科学学院
Fine mapping and characterization of a major QTL for grain weight on wheat chromosome arm 5DL
中国农业科学院国家小麦改良中心作物科学研究所
Camellia nitidissima Chi extract promotes adult hippocampal neurogenesis and attenuates chronic corticosterone-induced depressive behaviours through regulating Akt/GSK3β/CREB signaling pathway
香港大学李嘉诚医学院中医药学院药物生物技术国家重点实验室
Zeaxanthin Remodels Cytoplasmic Lipid Droplets via β3-Adrenergic Receptor Signaling and Enhances Perilipin 5-Mediated Lipid Droplet–Mitochondria Interactions in Adipocytes
吉林农业大学食品科学与工程学院
欢迎关注伯齐官方微信(微信公众号:Bio-Gene)
回复:BMG,查看相关视频
长按以下二维码可识别关注公众号
伯齐科技有限公司
Bio-Gene Technology Ltd.
广州伯齐生物科技有限公司
热线:176 2009 3784
www.bio-gene.com.cn
marketing@bio-gene.com.cn
香港 北京 上海 广州 成都 济南